Boutique Hotels in Panama City

Compare 4 top-rated boutique hotels in Panama City: Casco Viejo charm, bay-view infinity pools, and business district luxury. Book exclusive deals now!

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1-8 out of 8
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  • Popularity: high to low
8.7
Great9080 total reviews
our site & Booking.com
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1.5 km from City Centre700 m from Balboa Boutiques
Sushi LoungeConference RoomsTurkish Bath
  • 23 conference rooms for 1,300
  • Sushi Lounge Studio 50
  • Spa with Turkish bath
FromC$ 150 /nightSelect
8.9
Great943 total reviews
our site & Booking.com
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2.5 km from City Centre1.2 km from Multiplaza Pacific Mall
Infinity Pool24-Hour SpaCasino
  • Infinity-edge pool with panoramic views
  • 24-hour spa and fitness center
  • Pet-friendly luxury accommodations
FromC$ 195 /nightSelect
8.5
Great4974 total reviews
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1.9 km from City Centre400 m from Balboa Boutiques
Infinity PoolSky BarMajestic Casino
  • Infinity pool with panoramic city views
  • On-site casino and outlet mall
  • Top-floor sky bar with stunning views
FromC$ 512 /nightSelect
8.7
Great319 total reviews
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2.1 km from City Centre300 m from Coastal Beltway
Award-Winning SpaOutdoor PoolPool Bar
  • Award-winning spa with local ingredients
  • Ocean-view pool bar for cocktails
  • Complimentary shuttle within 2km radius
FromC$ 175 /nightSelect
8.7
Great677 total reviews
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5.1 km from City Centre400 m from Presidential Palace
Jazz ClubOutdoor PoolBanquet Facilities
  • Live jazz club on-site
  • Fusion cuisine and craft cocktails
  • Tailored wedding packages
FromC$ 356 /nightSelect
8.6
Great272 total reviews
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5.1 km from City Centre1.1 km from Panama Viejo Cathedral
Rooftop GardenSensory SpaExecutive Lounge
  • Sensory Spa by Clarins
  • Rooftop garden with swimming pool
  • Costa del Este business location
FromC$ 209 /nightSelect
8.5
Great4523 total reviews
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1.5 km from City Centre600 m from Parque Nacional Soberanía
Rooftop PoolGastro BarFitness Center
  • Rooftop pool with city views
  • On-site Gastro Bar Mediterranean
  • Strategic El Cangrejo location
FromC$ 88 /nightSelect
8.1
Great7417 total reviews
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1.9 km from City Centre400 m from Balboa Boutiques
Rooftop RestaurantTurkish BathCasino
  • Rooftop dining with panoramic skyline views
  • On-site casino with live entertainment
  • Spa featuring Turkish bath treatments
FromC$ 179 /nightSelect

Panama City's boutique hotels cater to travelers seeking personalized service and distinctive design. Options range from restored colonial buildings in Casco Viejo to sleek towers overlooking Panama Bay. Expect polished amenities like outdoor pools, fitness centers, and on-site dining, with room rates typically starting above $150 per night. Staying in Casco Viejo puts you near historic plazas and rooftop bars, while the business district offers convenient access to the waterfront promenade.

Top-rated options include the American Trade Hotel, a Casco Viejo landmark with a jazz bar and courtyard pool. The Waldorf Astoria Panama blends modern luxury with a full-service spa and two restaurants. The JW Marriott Panama on the bay features infinity pools and family-friendly facilities. Riu Plaza Panama rounds out the selection with reliable quality near the airport. All four hotels score 86 or higher on guest reviews, making them safe bets for a stylish Panama City stay.